Anti-Alpha-II Spectrin 803201 from BioLegend

Product Specs
ItemAnti-Alpha-II Spectrin
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number803201
Quantity200 µL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)-P, Immunocytochemistry (ICC)
Conjugate/TagUnconjugated
ReactivityHuman, Mouse, Rat, Drosophila
IsotypeIgG2b, Kappa
CloneD8B7
HostMouse
NCBI Full Gene Namespectrin alpha, non-erythrocytic 1
NCBI Gene AliasesDEE5, EIEE5, NEAS, SPTA2
ClonalityMonoclonal
Brand/TrademarkSIG-39702-200
Targetalpha-II Spectrin

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Proteomic and functional analyses of the periodic membrane skeleton in neuronsNature communicationsJune 9, 2022Zhou R, Han B, Nowak R, Lu Y, Heller E, Xia C, Chishti AH, Fowler VM, Zhuang X.1:500 for IF (Synaptic Systems, 188002), mouse anti-αII spectrin antibody 1:400 for IF (Biolegend, 803201, Clone D8B7), mouse anti-αII spectrin antibody 1:200 for IF (Encor Biotechnology, MCA-3D7, Clone 3D7),

(2) Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndromeNature geneticsJuly 1, 2021Cousin MA, Creighton BA, Breau KA, Spillmann RC, Torti E, Dontu S, Tripathi S, Ajit D, Edwards RJ, Afriyie S, et al.anti-neurofilament (1:200, clone SMI-312, #837904) and mouse anti-αII-spectrin (1:200, clone D8B7, #803201) from BioLegend, chicken anti-GFP (1:1,000, #GFP-1020) from Aves, and rabbit anti-OCT4 (1:500, #ab19857),

(3) Age-dependent ataxia and neurodegeneration caused by an αII spectrin mutation with impaired regulation of its calpain sensitivityScientific reportsMarch 31, 2021Miazek A, Zalas M, Skrzymowska J, Bogin BA, Grzymajło K, Goszczynski TM, Levine ZA, Morrow JS, Stankewich MC.

(4) NuMA1 promotes axon initial segment assembly through inhibition of endocytosisThe Journal of cell biologyFebruary 3, 2020Torii T, Ogawa Y, Liu CH, Ho TS, Hamdan H, Wang CC, Oses-Prieto JA, Burlingame AL, Rasband MN.F1804; RRIB:AB_262044), c-myc (BioLegend, Cat# 626802; RRID: AB_2148451), βII-spectrin (BioLegend, Cat# 803201; RRID: AB_2564660), βII-spectrin (R&D Systems, Cat# 612563; RRID: AB_399854), active Rab5-GTP (NewEast

(5) Mapping axon initial segment structure and function by multiplexed proximity biotinylationNature communicationsJanuary 3, 2020Hamdan H, Lim BC, Torii T, Joshi A, Konning M, Smith C, Palmer DJ, Ng P, Leterrier C, Oses-Prieto JA, et al.Systems Cat# 612563, RRID:AB_399854), mouse monoclonal antibody anti-α2-spectrin (1:1000; BioLegend Cat# 803201, RRID:AB_2564660). Mouse monoclonal anti-AnkyrinG (1:500; Cat# N106/36, RRID:AB_10673030 and N106/65,

(6) Defining new mechanistic roles for αII spectrin in cardiac functionThe Journal of biological chemistryJune 14, 2019Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud G, Gratz D, El Refaey M, et al.

(7) Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degenerationeLifeMay 1, 2019Wang G, Simon DJ, Wu Z, Belsky DM, Heller E, O'Rourke MK, Hertz NT, Molina H, Zhong G, Tessier-Lavigne M, et al.polyclonal anti-DLK,Genetex,Cat. # GTX124127,WB (1:500) Antibody,mouse anti-αII spectrin,BioLegend,Cat. # 803201; RRID: AB_2564660,WB (1:250) Antibody,rabbit anti-α-adducin,Abcam,Cat. # ab51130; RRID: AB_867519,WB

(8) Critical role of spectrin in hearing development and deafnessScience advancesApril 1, 2019Liu Y, Qi J, Chen X, Tang M, Chu C, Zhu W, Li H, Tian C, Yang G, Zhong C, et al.mouse monoclonal antibody that specifically targets αII-spectrin (clone D8BI7, BioLegend, catalog no. 803201) to label different isoforms of spectrin (11, 12, 17, 27). These cochlear tissues were subsequently

(9) αII Spectrin Forms a Periodic Cytoskeleton at the Axon Initial Segment and Is Required for Nervous System FunctionThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 22, 2017Huang CY, Zhang C, Ho TS, Oses-Prieto J, Burlingame AL, Lalonde J, Noebels JL, Leterrier C, Rasband MN.

(10) An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from DegenerationThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 22, 2017Huang CY, Zhang C, Zollinger DR, Leterrier C, Rasband MN.

(11) Stabilization and particle morphology of prune dwarf virusVirologySeptember 5, 1978Edward L. Halk, Robert W. Fulton

(12) [Usefulness of various graphometric methods in the evaluation of the neuroleptic threshold]Annales Academiae Medicae StetinensisJanuary 1, 1978J Pobocha

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Anti-Alpha-II Spectrin from BioLegend

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Anti-Alpha-II Spectrin from BioLegend

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